Mathematical and Computational Modeling of Tumor Development

Los Alamos National Laboratory Mathematics, 2005-06

Liaison(s): Yi Jiang
Advisor(s): Lisette dePillis
Students(s): Cris Cecka, Alan Davidson, Tiffany Head (PM: F), Dana Mohamed (PM: S), Liam Robinson

Computerized mathematical models of tumor growth can help increase understanding of cancer biology and potentially improve cancer treatment. Furthermore, such models can be used as predictive tools for studying the effects of chemotherapies upon tumor growth and creating more effective and precisely calibrated treatments. Our team explored vascular tumor growth by adding a blood vessel structure to a pre-existing avascular tumor model and then studying the effects of various in silico chemotherapy doses upon tumor growth.