Microfluidic Chip Quality Control System Improvement
January 1, 2018BD Biosciences Engineering, 2017-18
Liaison(s): Atul Madhusudan, Alireza Salmanzadeh Ph.D., Ruth Sung ’17
Advisor(s): Leah Mendelson
Students(s): Ramita Kondepudi (TL-F), Marissa Lee (TL-S), Jesus Villegas, Sati Smyth (F), Valerie Kwee (S), Russell Salazar (S)
The 2017-18 BD Biosciences Clinic Team improved a quality control (QC) system for an acoustic microfluidic chip. This chip separates white blood cells, which are of primary interest for the detection of autoimmune disorders, from the rest of blood. The QC system acquires images of flow through the chip and reports the accuracy of blood separation through image processing techniques. The team improved mechanical design and image processing components of this system to reduce manufacturing cost and processing time.