Researchers catalog large volumes of data into biological ontologies, graphs that denote relation- ships between biological descriptors, such as indicating that cystic fibrosis affects the lungs. The Monarch Initiative developed a program that utilizes ontologies to compare genetic diseases across species. This Clinic focuses on designing and implementing a faster algorithm via thresholding, a method of reducing the required calculations by only looking at data that meets a given level of significance, which naturally lends itself to parallel computation.