Optimization of a Recombinant Protein Product Through the Analysis of Filtration in the Production Process

Amgen Inc. (Global) Engineering, 2006-07

Liaison(s): Thomas Kelleher, Anthony Tran
Advisor(s): Anthony Bright, Elsie Pares-Matos (UPRM), Lorenzo Saliceti (UPRM)
Students(s): Felicia Nan (TL), Kenneth Estévez (UPRM-TL), Elisa Alfaro (UPRM), Solimar Díaz (UPRM), Mackenzie Miller, Heather Schalliol

Amgen wants the Amgen Global Clinic Team to explore sialidase inhibition and membrane filtration to optimize conditions for improving the amount of usable recombinant protein product. The HMC engineering students and the UPRM biotechnology students have been collaborating to understand sialidase activity as well as characterize different types of membranes within the filtration process. * (UPRM) University of Puerto Rico, Mayaguez, (S) Spring Semester